We have evaluated the toxicity of four glyphosate (G)-based herbicides in
Roundup (R) formulations, from 105 times dilutions, on three different
human cell types. This dilution level is far below agricultural
recommendations and corresponds to low levels of residues in food or
feed. The formulations have been compared to G alone and with its main
metabolite AMPA or with one known adjuvant of R formulations, POEA. HUVEC
primary neonate umbilical cord vein cells have been tested with 293
embryonic kidney and JEG3 placental cell lines. All R formulations cause
total cell death within 24 h, through an inhibition of the mitochondrial
succinate dehydrogenase activity, and necrosis, by release of cytosolic
adenylate kinase measuring membrane damage.
And it gets even better:
The deleterious effects are not proportional to G concentrations but rather depend on the nature of the adjuvants. AMPA and POEA separately and synergistically damage cell membranes like R but at different concentrations. Their mixtures are generally even more harmful with G. In conclusion, the R adjuvants like POEA change human cell permeability and amplify toxicity induced already by G, through apoptosis and necrosis. The real threshold of G toxicity must take into account the presence of adjuvants but also G metabolism and time-amplified effects or bioaccumulation.
Glysophate makes other chemicals even more toxic, and remember Glysophate
doesn’t break down rapidly and tends to accumulate in organisms.
Organisms such as you and your children.